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The active substance of Pamelor, namely Nortriptyline Hydrochloride, belongs to the tricyclic antidepressants class of medication. Its mechanism of action consists of an alteration of the chemical imbalance that may appear in parts of the patient's brain, an imbalance that causes several physical or emotional symptoms that affect the patient's general health condition and quality of life. Pamelor has a strong positive effect on correcting this imbalance thus effectively treating these symptoms.
Pamelor is typically indicated for the treatment of patients that suffer from depression, as it effectively treats the symptoms of this affection and improves the patients' general condition. Apart from that, Pamelor may also be successfully employed as part of the smoking cessation therapy, as it helps fight the withdrawal effects and as such may aid patients who wish to quit smoking. There are other uses for Pamelor that are not listed here. If your prescriber advises you to follow a therapy course with Pamelor and you are not sure why, it is best to ask him or her for more information.
Pamelor may not be administered to children or adolescents, or to patients that have recently suffered from heart attack. Individuals that are allergic to any of the active or inactive substances in Pamelor, or to any other tricyclic antidepressants or patients that are following a treatment with MAO inhibitors may not start taking Pamelor.
Other medical conditions may influence your ability to start a treatment with Pamelor. You should seek the advice of your physician if you have any liver, heart or kidney disorders, seizure disorders such as epilepsy, if you have diabetes, glaucoma, or hyperthyroidism (or if you are taking any thyroid gland related medication). Patients that are pregnant or breastfeeding, patients that have sustained heavy brain damage or head trauma, patients with bipolar disorders or mania, heavy drinkers or suicidal patients may require special consideration before starting to take Pamelor. Electroshock therapy and medication such as stimulants or sedatives may also interfere with the possibility of starting a treatment with Pamelor. You should inform your prescriber of any other medical condition you are suffering from before receiving a prescription for this pharmaceutical product.
Your prescriber will provide you with a complete set of guidelines for taking Pamelor in order to achieve the best results from the therapy. It is best that you closely follow the prescriber's indications. If the intake guidelines you are provided differ from any of the following information, you should take the drug as advised by your doctor.
The Pamelor tablets need to be taken whole, without crushing or chewing them. You may take them with food or with a full glass of water. In some situations, the prescriber may recommend you to use just half a tablet at a time - this is only possible for the 25 mg tablets. The smoking cessation treatment typically lasts for 3 to 6 months, while the treatment for depression may last much longer. You should continue taking the tablets for the full duration of the therapy, although you may experience an improvement in your condition much sooner. Do not stop taking Pamelor without your prescriber's consent.
For smoking cessation, the usual starting Pamelor dosage is of 25 mg per day increasing in time to a maximum of 75 mg to 100 mg per day. The treatment should begin two to four weeks before the date you actually stop smoking. If the drug is employed for the treatment of depression, the treatment usually consists of three to four daily intakes of 25 mg each. Elderly patients will receive a lower daily dose than the adult one, for example 25 to 50 mg. Your prescriber may advise you to use a different Pamelor dose than stated above. In this case, you should take the medication dosage that you have been indicated.
An overdose with Pamelor is often a severe condition and requires prompt medical attention. As such, if you think that you may have taken too much of the medicine you should immediately contact the local poisons center or call your personal health care professional. In severe cases you may need to go to the nearest clinic or hospital in order to receive emergency medical assistance.
You should keep a strict intake schedule for your Pamelor doses, as this may help reduce the chances of accidentally missing any intakes. However, if you happen to miss a dose of the medicine, it is best that you completely skip taking it. Do not attempt to make up for the missed dose by taking a larger dose of the medicine. It is recommended that you continue taking the medicine as regular, but you should inform your personal physician in order to determine if any corrective measures need to be taken.
Pamelor may cause a number of severe adverse reactions such as fainting, fits and seizures, severe chest pain, suicidal thoughts or allergic reactions. If you experience any of these you should immediately stop taking the drug and contact a trained health care professional. Other serious side effects of Pamelor include jaundice, vision disturbances, heart beat disorders, hallucinations or confusion, anxiety, agitation or a worsening of the depression. You should inform your personal physician of these and any other unwanted effects that may appear during your Pamelor treatment.
Pamelor may cause accidental drug reactions with other antidepressants (either tricyclic antidepressants, MAO inhibitors or SSR inhibitors), blood pressure medication, anticholinergics, sympathomimetics, thyroid medications, some heart drugs, Carbamazepine or Cimetidine. You should inform your prescriber of any other pharmaceutical products you are taking before starting your Pamelor therapy.
Other Brand Names
In some countries Pamelor may also be known as: